Journal: Current Research in Bioorganic & Organic Chemistry PDF
Published: April 09, 2019 Volume: 7 Issue: 2 Pages: 001-008
DOI: 10.29011/ 2639-4685. 100018 ISSN: 2573-2250
Authors: Alice Branton, Mahendra Kumar Trivedi, Dahryn Trivedi, Gopal Nayak and Snehasis Jana
Citation: Alice B, Mahendra K T, Dahryn T, Gopal N, Snehasis J. Complementary and Alternative Medicine: Evaluation of the Physicochemical and Thermal Properties of the Biofield Energy Treated Metronidazole. Glob J Pharmaceu Sci. 2019; 7(2): 555709. DOI: 10.19080/GJPPS.2019.07.555709
Abstract
Metronidazole is an antibiotic and is useful for antibacterial and antiprotozoal medication. In this research work, the impact of the Trivedi Effect® (Consciousness Energy Healing Treatment) on the physicochemical properties of metronidazole was evaluated using the modern analytical technique. Metronidazole sample was divided into two parts, one part of metronidazole was considered as a control sample (no Biofield Energy Treatment was provided); however, the other part of metronidazole, was exposed to the Consciousness Energy Healing Treatment remotely by a well-known Biofield Energy Healer, Alice Branton and termed as a treated sample. The peak intensities, as well as crystallite sizes of the treated metronidazole were significantly altered ranging from -97.25% to 463% and -83.18% to 123.79%, respectively; however, the average crystallite size was significantly decreased by 14.91% compared with the control sample. The particle size values in the treated metronidazole were significantly decreased by 14.69%(d10), 10.82%(d50), 19.14%(d90), and 16.88% {D (4,3)}; thus, the specific surface area was significantly increased by 24.7% compared to the control sample. The latent heat of fusion and latent heat of decomposition were decreased by 2.1% and 9.41%, respectively in the treated sample compared with the control sample. The total weight loss was increased by 2.56%; however, the residue amount was significantly decreased by 83.86% in the treated sample compared with the control sample. The maximum thermal degradation temperature was decreased by 3.53% in the treated sample compared with the control sample. Thus, the Consciousness Energy Healing Treatment might have generated a new polymorphic form of metronidazole which may offer better solubility, dissolution, and good bioavailability compared with the control sample. The Consciousness Energy Treated metronidazole would be very useful to design more efficacious pharmaceutical formulations for the better therapeutic response against bacterial and protozoal infection in the vagina, stomach, liver, skin, joints, brain, and respiratory tract, aspiration pneumonia, rosacea, fungating wounds, intra-abdominal infections, lung abscess, periodontitis, amoebiasis, oral infections, etc.
Conclusion
The experimental results showed that the Trivedi Effect®
(Consciousness Energy Healing Treatment) has a significant effect
on the particle size, surface area, and thermal properties of metronidazole. The peak intensities and crystallite sizes of the Biofield
Energy Treated metronidazole were significantly altered ranging from -97.25% to 463% and -83.18% to 123.79%, respectively; however, the average crystallite size was significantly decreased by 14.91% compared with the control sample. The particle size values in the Biofield Energy Treated metronidazole were significantly decreased by 14.69%(d10), 10.82%(d50), 19.14%(d90), and 16.88% {D (4,3)}; thus, the specific surface area was significantly increased by 24.7% compared to the control sample. The latent heat of fusion and latent heat of decomposition were decreased by 2.1% and 9.41%, respectively in the Biofield Energy Treated sample compared with the control sample.
The total weight loss was increased by 2.56%; however, the residue amount was significantly decreased by 83.86% in the Biofield Energy Treated sample compared with the control sample. The maximum thermal degradation temperature was decreased by 3.53% in the treated sample compared with the control sample. From the results, it can be concluded that the Trivedi Effect®-Consciousness Energy Healing Treatment might have generated a new polymorphic form of metronidazole which may offer better solubility, dissolution, and good bioavailability compared with the control sample. The Trivedi Effect®-Consciousness Energy Healing Treated metronidazole would be very useful to design better pharmaceutical formulations that might offer better therapeutic response against bacterial and protozoal infections in the vagina (bacterial vaginosis), stomach (giardiasis, pseudomembranous colitis), liver, skin, joints (pelvic inflammatory disease), brain, and respiratory tract, aspiration pneumonia, rosacea, fungating wounds, intra-abdominal infections, lung abscess, periodontitis, amoebiasis, oral infections, and infections caused by susceptible anaerobic organisms such as Bacteroides, Clostridium, Fusobacterium, Dracunculus, Peptostreptococcus, Helicobacter pylori, and Prevotella species, etc.
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