Published: 16-Apr-19 Volume: 2019 Issue: 1 Pages: 01-Aug
DOI: 10.29011/2574-7711.100078 ISSN: 2474-7711
Authors: Gopal Nayak, Mahendra Kumar Trivedi, Alice Branton, Dahryn Trivedi and Snehasis Jana
Citation: Nayak G, Trivedi MK, Branton A, Tivedi D, Jana S (2019) Complementary and Alternative Medicine: Impact of Consciousness Healing Treatment on the Characteristic Properties of Sulfamethoxazole. J Pharma Pharma Sci: JPPS-179. DOI: 10.29011/2574-7711.100079
Abstract
Sulfamethoxazole is the sulfonamide class of antibiotic that acts as a bacteriostatic agent against various bacteria. The current study was aimed to analyze the impact of the Consciousness Energy Healing Treatment (the Trivedi Effect®) on various properties of sulfamethoxazole by using different modern analytical techniques. For this, the sample was first divided into two parts, followed by considering one part as a control sample (no treatment was given). The second part was named as the Biofield Energy Treated sample that was remotely given the Consciousness Energy Healing Treatment by a renowned Biofield Energy Healer, Gopal Nayak. The particle size values were reduced by 14.35%(d10), 8.93%(d50), 7.84%(d90), and 9.24%{D(4,3)}; therefore, the specific surface area was increased by 9.68% in the treated sample compared to the control sample. The PXRD peak intensities and crystallite sizes were significantly altered ranging from -68.71% to 40.38% and -31.58% to 169.60%, respectively; however, the average crystallite size was significantly increased by 9.49% in the treated sample compared to the control sample. The residue weight and maximum thermal degradation temperature were increased by 2.12% and 3.25%, respectively in the treated sample compared with the control sample. The decomposition temperature, latent heat of fusion, and latent heat of decomposition were significantly increased by 11.44%, 48.27%, and 22.59%, respectively in the treated sample compared to the control sample. Thus, the Trivedi Effect®-Consciousness Energy Healing Treated sulfamethoxazole might have formed a new polymorph with reduced particle size and improved surface area and thermal stability. Hence, the use of the treated sulfamethoxazole might be more beneficial in terms of improved solubility, absorption, bioavailability, stability and also for designing the more efficacious pharmaceutical formulations for the treatment and prevention of various bacterial diseases, i.e., ear infections, urinary tract infections, shigellosis, travelers diarrhea, bronchitis, and pneumocystis-type of pneumonia, etc.
Conclusion
The study helped in analyzing the influence of the Trivedi Effect®-Consciousness Energy Healing Treatment on the physicochemical and thermal properties of sulfamethoxazole. The Biofield Energy Treated sample showed a reduction in their particle size values at d10, d50, d90, and D(4,3) by 14.35%, 8.93%, 7.84%, and 9.24%, respectively compared with the untreated sample. The resultant change was also observed in the specific surface area of the treated sulfamethoxazole sample that was significantly increased by 9.24% as compared to the control sample. Such significant changes in the particle size distribution might be helpful in improving the solubility and absorption of the treated sulfamethoxazole sample in comparison to the control sample. The PXRD data indicated the crystalline nature of both the samples however the Braggs angles of the characteristic peaks of the treated sample differ from the control sample. Also, the Biofield Energy Treated sample showed alterations in the peak intensities ranging from -68.71% to 40.38% along with -31.58% to 169.60% changes in the crystallite sizes as compared to the untreated sample. Moreover, the average crystallite size of the treated sample was increased by 9.49% after the Biofield Energy Treatment as compared to the control sample. The residue weight and the Tmax was increased by 2.12% and 3.25%, respectively in the treated sample compared with the control sample. The decomposition temperature, ?Hfusion, and ?Hdecomposition were significantly increased by 11.44%, 48.27%, and 22.59%, respectively in the treated sample compared to the control sample. Thus, the TGA/DTG and DSC data indicated the improved thermal stability of the treated sulfamethoxazole sample after the Biofield Energy Treatment compared to the untreated sample. Therefore, the study concluded the significant effect of the Trivedi Effect®-Consciousness Energy Healing Treatment on the physicochemical and thermal properties of sulfamethoxazole. The Biofield Energy Treatment might help in forming a new polymorph of sulfamethoxazole, which may have improved bioavailability and thermal stability compared with the untreated sample. Hence, the Consciousness Energy Healing Treated sulfamethoxazole might be considered to play a better role in the treatment and prevention of various bacterial diseases such as ear infections, urinary tract infections, shigellosis, travelers diarrhea, bronchitis, and pneumocystis-type of pneumonia, etc.
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