Materials Science

Evaluation of Physicochemical, Thermal, Structural, and Behavioral Properties of Magnesium Gluconate Treated with Energy of Consciousness (The Trivedi Effect®)

Written by Trivedi Effect | Mar 14, 2017 4:00:00 AM

Journal: Journal of Drug Design and Medicinal Chemistry PDF  

Published: 14-Mar-17 Volume: 3 Issue: 1 Pages: 5 – 17

DOI: 10.11648/j.jddmc.20170301.12 ISSN: 2472-355X (Print) 2472-3576 (Online)

Authors: Mahendra Kumar Trivedi, Alice Branton, Dahryn Trivedi, Gopal Nayak, Alan Joseph Balmer, Dimitrius Anagnos, Janice Patricia Kinney, Joni Marie Holling, Joy Angevin Balmer, Lauree Ann Duprey-Reed, Vaibhav Rajan Parulkar, Parthasarathi Panda, Kalyan Kumar Sethi, Snehasis Jana

Citation: Mahendra Kumar Trivedi, Alice Branton, Dahryn Trivedi, Gopal Nayak, Alan Joseph Balmer, Dimitrius Anagnos, Janice Patricia Kinney, Joni Marie Holling, Joy Angevin Balmer, Lauree Ann Duprey-Reed, Vaibhav Rajan Parulkar, Parthasarathi Panda, Kalyan Kumar Sethi, Snehasis Jana. Evaluation of Physicochemical, Thermal, Structural, and Behavioral Properties of Magnesium Gluconate Treated with Energy of Consciousness (The Trivedi Effect®). Journal of Drug Design and Medicinal Chemistry. Vol. 3, No. 1, 2017, pp. 5-17. doi: 10.11648/j.jddmc.20170301.12

 

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Abstract

Magnesium gluconate is a classical organometallic salt used for the prevention and treatment of magnesium deficiency diseases. The objective of the current research was to explore the influence of The Trivedi Effect® - Energy of Consciousness Healing Treatment (Biofield Energy Healing Treatment) on magnesium gluconate for the change in the physicochemical, structural, thermal and behavioral properties using PXRD, PSD, FT-IR, UV-vis spectroscopy, TGA, and DSC analysis. Magnesium gluconate was divided into two parts – one part was control, while another part was treated with The Trivedi Effect® - Energy of Consciousness Healing Treatment remotely by seven renowned Biofield Energy Healers and defined as the Biofield Energy Treated sample. The PXRD analysis exhibited significant alteration of the crystal morphology of the treated sample compared with the control sample. The crystallite size of the treated sample was remarkably changed from range -69.99% to 71.40% compared with the control sample. The average crystallite size was significantly decreased in the treated sample by 13.61% compared with the control sample. Particle size analysis revealed that the particle size in the treated sample at d10, d50, and d90 value was significantly decreased by 5.19%, 26.77%, and 18.22%, respectively compared with the control sample. The treated sample’s surface area was significantly enhanced (12.82%) compared with the control sample. The FT-IR and UV-vis analysis showed that the structure of the magnesium gluconate remained the same in both the treated and control samples. The TGA analysis revealed the four steps thermal degradation of the both samples and the total weight loss of the Biofield Energy Treated sample was increased by 0.55% compared with the control sample. The DSC analysis revealed that the melting temperature of the treated sample (171.72°C) was increased by 0.21% compared with the control sample (171.36°C). The latent heat of fusion was increased by 4.66% in the treated sample compared with the control sample. This result indicated that the thermal stability of treated sample was improved compared with the control sample. The current study infers that The Trivedi Effect® - Biofield Energy Healing might lead to a new polymorphic form of magnesium gluconate, which would be more soluble, bioavailable, and thermally stable compared with the untreated compound. Hence, the treated magnesium gluconate would be very useful to design better nutraceutical/pharmaceutical formulations that might offer better therapeutic responses against inflammatory diseases, immunological disorders, stress, aging and other chronic infections.

Conclusion

The current analysis anticipated the significant impact of The Trivedi Effect® - Energy of Consciousness Healing Treatment (Biofield Energy Healing Treatment) on physicochemical, structural, thermal and behavioral properties of magnesium gluconate. The PXRD analysis showed that the crystallite size of the treated magnesium gluconate was significantly altered from -69.99% to 71.40% with respect to the control sample. The average crystallite size was significantly decreased in the treated sample by 13.61% compared with the control sample. Overall, the PXRD analysis indicated the change of the crystal morphology in the treated sample compared with the control sample. Particle size analysis revealed that the particle size in the treated sample at d10, d50, and d90 value was significantly decreased by 5.19%, 26.77%, and 18.22%, respectively compared with the control sample. The surface area analysis revealed that the surface area of the treated sample was significantly increased by 12.82% compared with the control sample. The TGA analysis revealed the four steps thermal degradation of the both samples and the total weight loss of the treated sample was increased by 0.55% compared with the control sample. The DSC analysis revealed that the melting temperature of the treated sample (171.72°C) was increased by 0.21% compared with the control sample (171.36°C) with a 4.66% increase in the latent heat of fusion compared with the control sample. This result indicated that the thermal stability of the treated sample was improved compared with the control sample. The current analysis revealed that the treated magnesium gluconate would be a new polymorphic form of magnesium gluconate, which might have improved solubility, more bioavailability and long-term storage stability compared with the control sample. Thus, The Trivedi Effect® - Energy of Consciousness Healing Treatment, could be a useful approach in the design of better nutraceutical and/or pharmaceutical formulations that can offer significant therapeutic responses against various diseases such as diabetes mellitus, allergies and septic shock; stress-related disorders like sleep disorder, insomnia, anxiety, depression, Attention Deficit Disorder (ADD), Attention Deficit Hyperactive Disorder (ADHD), mental restlessness (mind chattering), brain frog, low libido, impotency, lack of motivation, mood swings, fear of the future, confusion, migraines, headaches, forgetfulness, overwhelm, loneliness, worthlessness, indecisiveness, frustration, irritability, chronic fatigue, obsessive/compulsive behavior and panic attacks; inflammatory diseases and immunological disorders like Lupus, Systemic Lupus Erythematosus, Hashimoto Thyroiditis, Type 1 Diabetes, Asthma, Chronic peptic ulcers, Tuberculosis, Hepatitis, Chronic active hepatitis, Celiac Disease (gluten-sensitive enteropathy), Addison Disease, Crohn's disease, Graves’ Disease, Pernicious and Aplastic Anemia, Sjogren Syndrome, Irritable Bowel Syndrome (IBS), Multiple Sclerosis, Rheumatoid arthritis, Chronic periodontitis, Ulcerative colitis, Chronic sinusitis, Myasthenia Gravis, Atherosclerosis, Vasculitis, Dermatitis, Diverticulitis, Rheumatoid Arthritis, Reactive Arthritis, Alopecia Areata, Psoriasis, Scleroderma, Fibromyalgia, Chronic Fatigue Syndrome and Vitiligo; aging-related diseases like cardiovascular disease, arthritis, cancer, Alzheimer’s disease, dementia, cataracts, osteoporosis, diabetes, hypertension, glaucoma, hearing loss, Parkinson’s Disease, Huntington’s Disease, Prion Disease, Motor Neurone Disease, Spinocerebellar Ataxia, Spinal muscular atrophy, Amyotrophic lateral sclerosis, Friedreich’s Ataxia and Lewy Body Disease, chronic infections and much more.