Journal: Organic and Medicinal Chemistry PDF
Published: April 12, 2019 Volume: 8 Issue: 3 Pages: 001-007
DOI: 10.19080/OMCIJ.2019.08.555738 ISSN: 2474-7610
Authors: Alice Branton, Mahendra Kumar Trivedi, Dahryn Trivedi, Gopal Nayak and Snehasis Jana
Citation: Alice B, Mahendra K T, Dahryn T, Gopal N, Snehasis J. Evaluation of the Physicochemical and Thermal Properties of Consciousness Energy Healing Treated Cefazolin Sodium. Organic & Medicinal Chem IJ. 2019; 8(3): 555738. DOI: 10.19080/OMCIJ.2019.08.555738
Abstract
Cefazolin sodium is a broad-spectrum first-generation cephalosporin antibiotic useful for the treatment of many bacterial infections. The aim of this research work was to estimate the impact of the Trivedi Effect® on the physicochemical and thermal properties of cefazolin using the modern analytical technique. Cefazolin sample was divided into control and treated parts. No Biofield Energy Treatment was provided to the control part of cefazolin; whereas, the treated part received Consciousness Energy Healing Treatment remotely by a distinguished Biofield Energy Healer, Alice Branton. The particle size values in the treated cefazolin were significantly increased by 11.44%(d10), 3.15%(d50), 2.35%(d90), and 2.42%{D(4,3)}; hence, the specific surface area was decreased by 4.54% compared to the control sample. The evaporation and decomposition temperature of the treated cefazolin was increased by 27.56% and 0.12%, respectively; however, the latent heat of evaporation and latent heat of decomposition was significantly altered by 1151.8% and -53.75%, respectively compared to the control cefazolin. The total weight loss was decreased by 6.57%, but the residue amount was significantly increased by 137.5% in the treated sample compared with the control sample. The maximum thermal degradation temperature of the 1st and 2nd peak was significantly altered by 5.58% and -28.66% in the treated sample compared with the control sample. The Consciousness Energy Healing Treatment might have introduced a new polymorphic form of cefazolin which may offer better powder flowability, smooth surface, and good thermal stability compared with the untreated sample. The treated cefazolin would be a more efficacious pharmaceutical formulation against cellulitis, urinary and respiratory tract infections, pneumonia, endocarditis, joint infection, genital infections, blood infections, etc.
Conclusion
The Trivedi Effect®-Consciousness Energy Healing Treatment has a significant effect on the particle size, surface area, and thermal properties of cefazolin sodium. The particle size values in the Consciousness Energy Healing Treated cefazolin sodium were significantly increased by 11.44%, 3.15%, 2.35%, and 2.42% at d10, d50, d90, and D(4,3), respectively compared to the control sample. Hence, the specific surface area was decreased by 4.54% in the Biofield Energy Treated cefazolin compared to the control sample. The evaporation and decomposition temperature of the Biofield Energy Treated cefazolin was increased by 27.56% and 0.12%, respectively compared with the control sample. However, the ?H evaporation was significantly increased by 1151.8%, and ?Hdecomposition was significantly decreased by 53.75% in the Biofield Energy Treated sample compared with the control sample. Simultaneously, the total weight loss was significantly reduced by 6.57%; hence the residue amount was significantly increased by 137.5% in the Biofield Energy Treated sample compared with the control sample. The Tmax was increased by 5.58% in the 1st peak and significantly decreased by 28.66% in the 2nd peak in the Biofield Energy Treated sample compared with the control sample. Overall, the thermal stability of the treated sample was improved compared with the control sample. Thus, the Consciousness Energy Healing Treatment might have generated a new form of cefazolin which would offer better powder flowability, smooth surface, and excellent thermal stability compared with the untreated sample. The Consciousness Energy Healing Treated cefazolin would be very useful to design better pharmaceutical formulations that may offer better therapeutic response against cellulitis, UTI, respiratory tract infections, pneumonia, endocarditis, joint infection, biliary tract infections, genital infections, blood infections (sepsis), and also prevent group B streptococcal disease at the time of delivery and before surgery, etc.
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