Journal: International Journal of Pharmacognosy and Chinese Medicine PDF
Published: February 4, 2019 Volume: 3 Issue: 1
DOI: 10.23880/ipcm-16000154 ISSN: 2576-4772
Authors: Alice Branton, Trivedi MK, Trivedi D, Nayak G and Jana S
Citation: Branton A, et al. Study of the Effect of Consciousness Energy Healing Treatment on the Natural Product Berberine Chloride. Int J Pharmacogn Chinese Med 2019, 3(1): 000154
Abstract
Berberine chloride is an isoquinoline alkaloid that has antimicrobial activity against bacteria, viruses, chlamydia, fungi, protozoans, and helminths, etc. The study was designed with the aim to evaluate the influence of the Trivedi Effect®Consciousness Energy Healing Treatment on the physicochemical and thermal properties of berberine chloride by using modern analytical techniques. For this study, the berberine chloride sample was divided into two parts among which, one part was named as control as no Biofield Energy Treatment was given to it; while the other part received the Consciousness Energy Healing Treatment remotely by a renowned Biofield Energy Healer, Alice Branton and named as the Biofield Energy Treated sample. The PXRD results revealed some changes in the Braggs angle of peaks along with 7.24% to 188.78% alterations in the peak intensities and -65.88% to 135.42% changes in the crystallite sizes of the treated sample. Also, there was 1.91% decrease in the average crystallite size of the treated sample compared to the control sample. The particle size of the treated sample was significantly reduced by 20.16% (d10), 17.21% (d50), 27.53% (d90), and 27.36% {D(4,3)}; along with 15.31% increase in the specific surface area compared with the control sample. The total weight loss was significantly reduced by 25.81%; however, the residue amount was significantly increased by 55.04% in the treated sample compared to the control sample. Besides, the DSC thermogram showed four peaks, in which the peak temperatures of the treated sample corresponding to 1st, 2nd, 3rd, and 4th peak were altered by -2.26%, 3.55%, 4.50%, and -0.69%, respectively. Moreover, the latent heat for 1st, 2nd, 3rd, and 4th peak of the treated sample were significantly reduced by 24.04%, 42.44%, 44.26%, and 47.78%, respectively, compared with the control sample. The results showed that the Trivedi Effect®-Consciousness Energy Healing Treatment might help in improving the solubility, absorption, and bioavailability of berberine chloride compared with the control sample. Hence
Conclusion
The current study revealed the significant impacts of the Trivedi Effect®-Consciousness Energy Healing Treatment on the physiochemical properties of berberine chloride. The PXRD peak intensities and the crystallite sizes of the Biofield Energy Treated sample were altered ranging from -7.24% to 188.78% and -65.88% to 135.42%, respectively, compared to the control sample. The Biofield Energy Treated sample also showed changes in the average crystallite size, which was observed to be reduced by 1.91% compared with the control sample. Such changes might happen due to the formation of the novel polymorph of berberine chloride after the Biofield Energy Treatment that may affect the performance of drug within the body.
The study also revealed that the particle sizes of the Biofield Energy Treated sample were significantly decreased at d10, d50, d90, and D(4,3) by 20.16%, 17.21%, 27.53%, and 27.36%, respectively compared with the control sample. It further significantly increased the specific surface area of the Biofield Energy Treated berberine chloride by 15.31%, compared with the control sample.
These changes pertaining to the particle size and surface area of the Biofield Energy Treated sample may help in enhancing the solubility, dissolution, and bioavailability parameters of berberine chloride in comparison to the control sample. The total weight loss was significantly reduced by 25.81%; however, the residue amount was significantly increased by 55.04% in the treated sample compared to the control sample. Besides, the DSC thermogram showed four peaks, in which the peak temperatures of the treated sample corresponding to 1st, 2nd, 3rd, and 4th peak were altered by -2.26%, 3.55%, 4.50%, and -0.69%, respectively.
Moreover, the latent heat for 1st, 2nd, 3rd, and 4th peak of the treated sample were significantly reduced by 24.04%, 42.44%, 44.26%, and 47.78%, respectively, compared with the control sample. The overall study concluded that the Trivedi Effect®-Consciousness Energy Healing Treatment may help in producing a new polymorphic form of berberine chloride that might improve its solubility, dissolution, absorption and bioavailability profile along with the thermal stability, compared with the control sample.
Therefore, the Consciousness Energy Healing Treated berberine chloride may be used in formulating the novel pharmaceutical/nutraceutical products that might prove to be more clinically effective for the treatment of various microbial diseases and disorders such as diarrhea, gastroenteritis, ailments related to skin and eye, hypertension, tumor, malaria, hyperglycemia, inflammation, arrhythmia, fungal and plasmodial infections, etc.
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