The Effect of Consciousness Energy Healing Treatment on Physico-chemical and Thermal Properties of 6-Mercaptopurine

6-Mercaptopurine is an antimetabolite antineoplastic agent. The objective of the study was to evaluate the impact of the Trivedi Effect®-Consciousness Energy Healing Treatment on physicochemical and thermal properties of 6-mercaptopurine using the modern analytical technique. The 6-mercaptopurine sample was divided into two parts, one part of mercaptopurine was considered as a control sample, while the other part was subjected to the Biofield Treatment remotely by a renowned Biofield Energy Healer, Alice Branton and termed as a treated sample. The PXRD peak intensities and crystallite sizes were significantly altered ranging from -63.38% to 3.85% and -55.26% to 228.26%, respectively, whereas the average crystallite size was significantly increased by 8.16% in the treated mercaptopurine compared with the control sample. The particle size values were significantly decreased by 26.63% (d10), 24.43% (d50), 17.56% (d90), and 21.41% [D (4,3)] and the specific surface area was significantly increased by 38.57% in the treated sample compared to the control sample. The latent heat of fusion was significantly increased by 49.97% in the treated sample compared to the control sample. The total weight loss was decreased by 11.45%; whereas the residue amount was significantly increased by 160.07% in the treated sample compared with the control sample. The results indicated that the Trivedi Effect® might lead to the generation of a new polymorphic form of mercaptopurine which would offer better solubility, absorption, and bioavailability compared with the control sample, which would be useful in designing novel pharmaceutical formulations for the better therapeutic responses against leukemia, Crohn’s disease, ulcerative

The experimental results confirmed that the Trivedi Effect®- Consciousness Energy Healing Treatment has significant effects on the particle size, surface area, and thermal properties of 6-mercaptopurine. The PXRD analysis indicated that the peak intensities and crystallite sizes of the Biofield Energy Treated mercaptopurine were significantly altered in the range from -63.38% to 3.85% and -55.26% to 228.26%, respectively compared to the control sample. The average crystallite size of the Biofield Energy Treated mercaptopurine was significantly increased by 8.16% compared with the control sample. The particle size values in the Biofield Energy Treated mercaptopurine were significantly decreased by 26.63%, 24.43%, 17.56%, and 21.41% at d10, d50, d90, and D (4,3) compared to the control sample. Therefore, the specific surface area of the Biofield Energy Treated mercaptopurine was significantly increased by 38.57% compared to the control sample. The significant increase in the ?Hfusion by 49.97% in the Biofield Energy Treated mercaptopurine indicated that the thermal stability of the Biofield Energy Treated sample was more compared to the control sample. The total weight loss was decreased by 11.45%; however, the residue amount was significantly increased by 160.07% in the Biofield Energy Treated sample compared with the control sample. The Trivedi Effect®-Consciousness Energy Healing Treatment might lead to the generation of a new polymorphic form of mercaptopurine which would offer better solubility, dissolution, absorption, and bioavailability compared with the control sample. The Trivedi Effect®-Consciousness Energy Healing Treated mercaptopurine would be more efficacious in pharmaceutical formulations that might offer better therapeutic response against acute lymphocytic leukemia, chronic myeloid leukemia, Crohn’s disease, and ulcerative colitis, etc.