The Energy of Consciousness Healing Treatment: Impact on Physicochemical and Thermal Properties of L-Tryptophan

L-tryptophan is an essential amino acid that helps in growth in infants and aids nitrogen balancing in adults, etc. This study helps in evaluating the impact of the Trivedi Effect® on the physicochemical and thermal properties of L-tryptophan with the help of various analytical techniques. One part of L-tryptophan sample didn’t receive any treatment and was called the control sample, while the other part was given the Biofield Treatment remotely by a renowned Biofield Energy Healer, Gopal Nayak and named as the treated sample. The particle size values were significantly altered by -43.95%(d10), -6.28%(d50), 9.97%(d90), and 10.36%[D(4,3)]; thus, the specific surface area was significantly increased by 51.61% in the treated sample compared to the control sample. The PXRD peak intensities and crystallite sizes were significantly altered ranging from -61.17% to 385.06% and -48.52% to 3.76% respectively, however, the average crystallite size was significantly reduced by 26.03% in the treated sample compared to the control sample. The total weight loss was significantly increased by 17.35%; additionally, the residual amount was significantly reduced by 83.95% in the treated sample compared to the control sample. The ?Hfusion was significantly increased by 10.43% in the treated sample compared to the control sample. Thus, the Biofield Treatment produced the novel polymorph of L-tryptophan that might give better solubility, bioavailability, and thermal stability in nutraceutical/pharmaceutical formulations with and an improved drug profile.

The study results showed that there has been a significant impact on the crystallite size, particle size, particle area, and thermal properties of the Trivedi Effect®-Consciousness Energy Healing treated L-tryptophan in comparison to the untreated sample. The particle size analysis indicated the altered particle size values of the Biofield Energy Treated L-tryptophan sample at d10, d50, d90, and D(4,3) after the Biofield Energy Treatment were -43.95%, -6.28%, 9.97%, and 10.36%, respectively compared to the control sample. Additionally, the surface area of the Biofield Energy Treated sample was observed to be significantly increased by 51.61% as compared to the untreated L-tryptophan sample. It indicated there might be the improvement in the solubility and absorption profile of the Biofield Energy Treated sample in comparison to the untreated sample. The PXRD data showed significant alterations in the Bragg’s angles of the highest intensity peak along with the other characteristic peaks of the Biofield Energy Treated sample, when compared with the control sample. Apart from that, the Biofield Energy Treated sample revealed significant changes in the peak intensities and crystallite sizes of the peaks present in the diffractogram ranging from -61.17% to 385.06% and -48.52% to 3.76%, respectively compared to the control sample. The Biofield Energy Treatment on the L-tryptophan sample resulted in the significant reduction in the average crystallite size by 26.03% as compared to the control sample. Thus, the PXRD data revealed some major changes in the crystalline structure and properties of the L-tryptophan sample after the Biofield Energy Treatment and suggests the possibility of generation of a new polymorph of L-tryptophan. The thermal analysis using TGA/DTG studies suggests significant increase (17.35%) in the total weight loss of the treated sample during the thermal degradation, which resulted in 83.95% reduction in the residual amount as compared to the control L-tryptophan sample. Moreover, the DTG thermogram of both, the control and the treated sample showed two peaks. The Tmax corresponding to 1st and 2nd peak of the treated sample were observed to be slightly reduced by 0.33% and 1.43%, respectively, compared to the untreated sample. Thus, the thermal analysis revealed increased thermal degradation of the Biofield Energy Treated sample in comparison to the untreated sample. The ?Hfusion of the Biofield Energy Treated L-tryptophan sample was observed to be significantly increased by 10.43% in comparison to the control sample. The Trivedi Effect®-Consciousness Energy Healing Treatment of the L-tryptophan sample might result in the generation of new polymorph with improved solubility, absorption, and bioavailability profile along with altered thermal stability as compared with the untreated sample. Therefore, the Biofield Energy Treated L-tryptophan might be useful for the development of better bioavailable formulation, which can be used for the prevention and treatment of various diseases such as mental health disorders, bruxism, facial pain, seasonal affective disorder, premenstrual dysphoric disorder, sleep apnoea, attention deficit-hyperactivity disorder (ADHD), anxiety, obsessive-compulsive disorder, depression, bipolar disorder, and sleep apnea, etc.